+86-0574-27803775
sales@nbicoe.com 

Facebook
Twitter
Google+
LinkedIn
Pinterest

  • Home
  • About Us
  • Products
    • Microscopy
      • Biological Microscopes
        • Educational Microscopes
        • Infinity Biological Microscopes
        • Inverted Microscopes
        • Multi-viewing Microscopes
        • Phase Contrast Microscopes
        • Digital Biological Microscopes
      • Microscope Slides & Accessories
        • Human Histology Slides
        • Human Pathology Slides
        • Parasitology Slides
        • Botany Slides
        • Animal Slides
        • Microorganisms & Bacteria
      • Stereo Microscopes
        • Comparison Forensic Microscope
        • Educational Stereo
        • Greenough Zoom Stereo
        • CMO (Galilean) Zoom Stereo
        • Eyepieceless Stereo
        • Digital Stereo
        • Stands & Arms of Stereo Microscope
      • Fluorescence Microscopes
        • Epi-LED Fluorescence
        • Epi-Fluorescence
        • Inverted Fluorescence
      • Metallurgical Microscopes
      • Polarizing Microscopes
      • Digital Microscopes
        • Tabletop Digital Microscope
        • Portable Digital Microscope
      • Comparison Microscope
      • Motorized Scanning Microscope
      • Industrial Monocular Microscope
        • Monocular Zoom Objective Series
        • Digital Monocular Zoom Microscope Series
        • 3D Rotated Series
      • 3D Digital Inspection
      • Confocal Microscope
      • Measuring Microscope
      • Video Microscope Unit & System
      • Micromanipulation System
      • WiFi Interactive Classroom System
      • Digital Cameras & Tablets
        • USB2.0 CMOS Cameras
        • USB3.0 CMOS Cameras
        • Wifi Cameras
        • VGA/HDMI Cameras
        • USB2.0 CCD Cameras
        • USB3.0 CCD Cameras
        • Cooling Camera
        • Tablets
      • Microscope Light
      • Others
        • Microscope Adapters for Camera
    • Scanning Electron Microscopy (SEM)
    • Measurement Systems
    • Machine Vision
      • Machine Vision Camera
      • Machine Vision Light
        • Line Lights
        • Ring Lights
        • Bar Lights
        • Coaxial Lights
        • Backlights
        • UV/IR Lights
        • Strobe Lights
        • Diffused Lights
        • Spot Lights
        • AOI Lights
        • Multi-Colored Lights
        • Water Proof Lights
        • Structured Lights
    • Gel Documentation System
    • In Vivo Imaging System
    • Cell Culture Imaging System
    • Digital Pathology Slide Scanner
    • Refractometer
      • Handheld Refractometer
      • Digital Refractometer
        • Portable Digital Refractometer
        • Tabletop Digital Refractometer
        • Mini Pen-type Digital Refractometer
      • Abbe Refractometer
    • Automatic Cell Counter
    • Polarimeter
      • Disc Polarimeter
      • Semi-Auto Polarimeter
      • Auto Polarimeter
    • Melting Point Apparatus
    • Particle Size & Zeta Potential Analyzer
  • News
  • Contact
  • Feedback
  • Download
  • Featured Products

VIVO-LSI Series Laser Speckle Imaging System

Home In Vivo Imaging System VIVO-LSI Series Laser Speckle Imaging System

VIVO-LSI Series Laser Speckle Imaging System

In Vivo Imaging System2022-05-02n50

Description

Description

VIVO-LSI is based on the LSCI (Laser Speckle Contrast Analysis Imaging ) technology design, non-invasive with non-contact, high time resolution, high spatial resolution, and full-field rapid imaging. It provides real-time dynamic blood flow monitoring and recording for research, perfusion evaluation, such as MCAO, cerebral blood flow. compared with lase doppler imaging, it can realize full field video imaging function.

 

Applications:

  • Cerebral blood flow, MCAO model
  • Cortical Spreading Depression (CSD)
  • Hind/Critica Limb Ischaemia (HLI)/(CLI)
  • Neuro-Vascular Coupling
  • Burn Assessment, Traumatic Brain Injury(TBI) and Sepsis

 

Features

The VIVO-LSI can be used to measure the microcirculation of any exposed superficial vessels, such as the cortex, mesentery, lower limbs, and spinal cord. It is a popular choice and has been used in more than 100 colleges, universities, and research institutes throughout the world. It offers:

  • Non-invasive, real-time, full-field imaging with high-definition; no need for scanning, no need of contact, no need of contrast for imaging
  • 12x Optical lens, autofocus, electrical zoom, allows researchers to adjust the image area as they need
  • Built-in Basler camera delivering high definition and high speed imaging. Image resolution up to 2048 x 2048 pixels and high frame rate speed of up to 120 frames per second
  • Dual 3.0 USB interface for fast data transmission, high frame rate and high resolution
  • A Thorlabs laser is used to output laser with good coherence to ensure the stability of baseline data and obtain the fluctuation data of real blood perfusion
  • Blood flowmeter (the volume of blood perfusion expressed as conventional unit PU) to observe the relative changes in the velocity of blood flow by combining image data with perfusion data
  • The global PU value is adopted to quantify the values of blood perfusion and obtain the objective data changes in the velocity of blood flow.
  • Combining the image data and perfusion data, the velocity of blood flow can be observed by the pictures, and the relative velocity of blood flow can be judged by different colors. (Perfusion Unit)
  • Hardware structures including instruction laser and Cardan gimbals and humanized software operation mode make the whole system easy to use

 

What is Speckle Contrast Analysis?

Speckle flow techniques are based on the changes over time of the dynamic speckle pattern generated by motion in the sample. In these techniques, this changing speckle pattern is recorded with a camera that has an integration time in the order of the speckle decorrelation time (i.e., in the millisecond range). Due to the long integration time compared to the typical decorrelation time of the speckle pattern, the speckle pattern will be blurred in the recorded image. The level of blurring is quantified by the speckle contrast.

 

Why choose the VIVO-LSI

 

Specifications

Model VIVO-LSI
Scale 0 – 5000PU
Imaging acquisition rate Up to 120 FPS
Working distance 10 – 35 cm
Image size 1.57 × 1.57mm – 90 × 90mm
Image camera pixels 4.2 million(2048 × 2048)
Max resolution Up to 3μm/pixel
Zoom range 12× optical zoom lens with auto-focus
Wavelength 785nm

 

Case Study

Use the laser speckle to observe changes in cerebral blood flow after lymphatic ablation and quantitative analysis

  • Use the laser speckle to observe changes in cerebral blood flow after lymphatic ablation, and quantitative analysis. Explore whether meningeal lymphatics are involved in clearing extravasated erythrocytes in CSF after SAH.

 

Real-time monitor the regional velocity and distribution of blood flow and perfused vessel for sciatic nerve and foot pads

  • Use LSCI to real-time detect regional velocity and distribution of blood flow and perfused blood vessel of sciatic nerve and foot pads, and also analyze image to better evaluate the therapeutic effect of small molecule substances on diabetes.

 

Detect the changes of the cerebral cortex blood perfusion of a Cardiac arrest (CA) and Return of spontaneous circulation (ROSC) mouse model

  • The main purpose of the UPR is to restore ER homeostasis, and promote cell survival. It has been well established that brain I/R insult caused by transient ischemic stroke or CA/resuscitation leads to ER stress and subsequent activation of the UPR. The previous study has demonstrated that the XBP1s/HBP/O-GlcNAc axis functions in the brain, and is activated after ischemic stroke or CA (6, 8). Here, the goal was to clarify the effect of this axis on functional outcome after CA in young and aged mice.

 

Inquiry Us





Product Categories

  • Microscopy
    • Biological Microscopes
      • Educational Microscopes
      • Infinity Biological Microscopes
      • Inverted Microscopes
      • Multi-viewing Microscopes
      • Phase Contrast Microscopes
      • Digital Biological Microscopes
    • Phase Contrast Microscope
    • Microscope Slides & Accessories
      • Animal Slides
      • Botany Slides
      • Microorganisms & Bacteria
      • Human Histology Slides
      • Human Pathology Slides
      • Parasitology Slides
    • Stereo Microscopes
      • Educational Stereo
      • Greenough Zoom Stereo
      • CMO (Galilean) Zoom Stereo
      • Comparison Forensic Microscope
      • Eyepieceless Stereo
      • Digital Stereo
      • Stands & Arms of Stereo Microscope
    • Fluorescence Microscopes
      • Epi-LED Fluorescence
      • Epi-Fluorescence
      • Inverted Fluorescence
    • Metallurgical Microscopes
    • Confocal Microscope
    • Digital Microscopes
      • Tabletop Digital Microscope
      • Portable Digital Microscope
    • Comparison Microscope
    • Motorized Scanning Microscope
    • Measuring Microscope
    • Video Microscope Unit & System
    • Micromanipulation System
    • Industrial Monocular Microscope
      • Monocular Zoom Objective Series
      • Digital Monocular Zoom Microscope Series
      • 3D Rotated Series
    • WiFi Interactive Classroom System
    • Polarizing Microscopes
    • Digital Cameras & Tablets
      • VGA/HDMI Cameras
      • USB2.0 CCD Cameras
      • USB3.0 CCD Cameras
      • Cooling Camera
      • Tablets
      • USB2.0 CMOS Cameras
      • USB3.0 CMOS Cameras
      • Wifi Cameras
    • 3D Digital Inspection
    • Microscope Light
    • Others
      • Microscope Adapters for Camera
  • Polarimeter
    • Disc Polarimeter
    • Semi-Auto Polarimeter
    • Auto Polarimeter
  • Automatic Cell Counter
  • Melting Point Apparatus
  • Optomechanics
    • Optomechanical Components
      • Piezo Objective Scanner
  • Imaging Components
    • DIY Components for Building of Microscopy, Imaging System
    • Piezo Objective Scanner
  • Featured Products
  • Scanning Electron Microscopy (SEM)
  • Measurement Systems
  • Machine Vision
    • Machine Vision Camera
    • Machine Vision Light
      • Line Lights
      • Ring Lights
      • Bar Lights
      • Coaxial Lights
      • Backlights
      • UV/IR Lights
      • Strobe Lights
      • Diffused Lights
      • Spot Lights
      • AOI Lights
      • Multi-Colored Lights
      • Water Proof Lights
      • Structured Lights
  • Gel Documentation System
  • In Vivo Imaging System
  • Cell Culture Imaging System
  • Digital Pathology Slide Scanner
  • Refractometer
    • Abbe Refractometer
    • Handheld Refractometer
    • Digital Refractometer
      • Portable Digital Refractometer
      • Tabletop Digital Refractometer
      • Mini Pen-type Digital Refractometer
  • Particle Size & Zeta Potential Analyzer

 

Latest Post

  • ICOE: Optics Expert
    2017-03-20
  • News Six: weolcome to our website
    2017-03-20
  • News Five: weolcome to our website
    2017-03-20

Email Newsletters

Welcome to subscribe email newsletter to us, get the lastest products and news information from us!

Contact Us

912598829

+86-0574-27803775

sales@nbicoe.com

sales@nbicoe.com

COB 1704, Century Oriental Plaza, Yinzhou District, Ningbo, China

Mobile Website

NINGBO ICOE COMMODITY CO., LTD, YOUR OPTICA EXPERTS